Aeid Igbaria

I am a senior Lecturer (Assistant Professor) in the Department of Life Sciences at the Ben Gurion University of the Negev (BGU).

I obtained My Ph.D. from the University of Paris SUD-11, France. After my Ph.D., I had my postdoctoral training at the University of California San Francisco (UCSF) and then I moved as a young researcher to INSERM-U1442 Rennes, France. I became a faculty member in 2020. 

In my lab, I study the behavior of proteins in one of the cellular compartments called the Endoplasmic Reticulum (ER). The ER is an organelle within the cell that is responsible for synthesis, folding and posttranslational modifications of protein of the secretory pathway. Perturbations in the proper function of the ER were found recently to be associated with the development of different human diseases including Diabetes (T1D and T2D), neurodegenerative diseases, aging, and cancer. My research interest is to understand how changes in protein homeostasis inside the cell (focusing mainly on ER proteins) contribute to the development of human diseases in general and to Cancer in particular. We mainly focus on how ER resident proteins change their location within the cell and how this change of address makes them acquire new functions that can lead to cancer.